£399.00
DUTCH Plus + Cortisol Awakening Response
DUTCH Plus is an advanced hormone test that evaluates 35 sex and adrenal hormones, along with their metabolites, to provide a deep and accurate understanding of your body’s hormonal balance and stress response.
What sets DUTCH Plus apart is its focus on the Cortisol Awakening Response (CAR) – a critical marker of how your body reacts to stress right after waking. By analysing both free cortisol and free cortisone patterns, this test offers unmatched insights into your hypothalamic-pituitary-adrenal (HPA) axis function.
DUTCH Plus also includes:
- 8-OHdG – A marker of oxidative stress and DNA damage
- Melatonin (6-OHMS) – To evaluate sleep-wake cycles
- 9 Organic Acids – Including markers for:
- B-vitamin status
- Glutathione (antioxidant capacity)
- Dopamine levels
- Neuroinflammation
Whether you’re struggling with fatigue, sleep issues, mood swings, or other hormone-related symptoms, DUTCH Plus provides the data needed for truly personalised treatment strategies.
- 2-Methoxy-E1
- 2-OH-E1
- 2-OH-E2
- 4-OH-E1
- 4-OH-E2
- 5-Hydroxyindolacetate (5HIAA)
- 5a-Androstanediol
- 5a-Dihydrotestosterone (5a-DHT)
- 5b-Androstanediol
- 8-hydroxy-2’-deoxyguanosine
- 16-OH-E1
- 24hr Free Cortisol
- 24hr Free Cortisone
- A-pregnanediol
- A-Tetrahydrocortisol (a-THF)
- Androsterone
- B-Hydrioxyisovalerate
- B-Tetrahydriocortisone (b-THE)
- B-Tetrahydrocortisol (b-THF)
- Cortisol (Saliva)
- Cortisone (Salvia)
- Dehydroepiandrosterone Sulphate (DHEA-S)
- Dihydrotestosterone (DHT)
- Epi-Testosterone
- Estradiol (E2)
- Estriol (E3)
- Estrone (E1)
- Ethiocholanolone
- Homogentisic Homovanillic Acid (HVA)
- Indican
- Melatonin
- Metabolized cortisol (THF+THE)
- Methylation activity (2-Me-E1/2-OH-E1)
- Methylmalonic Acid (MMA)
- Progesterone (Pg) (calculated equivalent)
- Pyroglutamate
- Quinolinate (Neuroinflammation marker)
- Testosterone
- Total Dehydroepiandrosterone (DHEA)
- Total Oestrogen (Estrogen)
- Vanillmandelic Acid (VMA)
- Zanthurenate
Choose a test location:
What's included in the test?
-
Oestrogens & Metabolites (11)
- Estrone (E1)
- Estradiol (E2)
- Estriol (E3)
- 2-OH-E1
- 2-OH-E2
- 4-OH-E1
- 4-OH-E2
- 16-OH-E1
- 2-Methoxy-E1
- Total Oestrogen (Estrogen)
- Methylation activity (2-Me-E1 / 2-OH-E1)
-
Androgens & Metabolites (8)
- Testosterone
- Dihydrotestosterone (DHT)
- 5a-Dihydrotestosterone (5a-DHT)
- Epi-Testosterone
- Androsterone
- Etiocholanolone
- 5a-Androstanediol
- 5b-Androstanediol
-
Progesterone & Metabolites (3)
- Progesterone
- 𝛼-Pregnanediol
- β-Pregnanediol
-
DHEA & Metabolites (2)
- Dehydroepiandrosterone Sulfate (DHEA-S)
- Total Dehydroepiandrosterone (DHEA)
-
Free Hormones (4)
- 24hr Free Cortisol
- 24hr Free Cortisone
- Cortisol (Saliva)
- Cortisone (Saliva)
-
Metabolised Cortisol & Cortisone (7)
- Metabolized Cortisol (THF + THE)
- 𝛼-Tetrahydrocortisol (a-THF)
- β-Tetrahyrodcortisol (b-THF)
- β-Tetrahydrocortisone (b-THE)
- 5-Hydroxyindolacetate (5HIAA) – Serotonin metabolism
- Vanillmandelic Acid (VMA) – Epinephrine/Norepinephrine metabolism
- Homogentisic Homovanillic Acid (HVA) – Dopamine metabolism
-
Organic Acids (5)
- Methylmalonic Acid (MMA) – B12 status
- Pyroglutamate – Glutathione metabolism
- β-Hydroxyisovalerate – Biotin (B7) status
- Xanthurenate – Vitamin B6 metabolism
- Indican – Intestinal dysbiosis / protein putrefaction marker
-
Oxidative Stress and Inflammation (3)
- 8-hydroxy-2′-deoxyguanosine (8-OHdG) – Oxidative DNA damage
- Quinolinate – Neuroinflammation marker
- Melatonin (6-OHMS) – Sleep-wake regulation
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